Papers
* : Equally Contributed
† : Corresponding Author
Engineering TALE-linked deaminases to facilitate precision adenine base editing in mitochondrial DNA.
Sung-Ik Cho*, Kayeong Lim*, Seongho Hong*, Jaesuk Lee, Annie Kim, Chae Jin Lim, Seungmin Ryou, Ji Min Lee, Young Geun Mok, Eugene Chung, Sanghun Kim, Seunghun Han, Sang-Mi Cho, Jieun Kim, Eun-Kyoung Kim, Ki-Hoan Nam, Yeji Oh, Minkyung Choi, Tae Hyeon An, Kyoung-Jin Oh, Seonghyun Lee† and Hyunji Lee† and Jin-Soo Kim†. Cell 2024 Jan 4;
IF=66.850
Precise Base Editing Without Unintended Indels in Human Cells and Mouse Primary Myoblasts.
Da Eun Yoon, Na-Rae Kim, Soo-Ji Park, Tae Yeong Jeong, Bokkee Eun, Yongcheol Cho, Soo-Yeon Lim, Hyunji Lee, Je Kyoung Seong and Kyoungmi Kim†. Experimental and Molecular Medicine 2023 Dec 1; IF=12.172
Recent Research Trends in Stem Cells Using CRISPR/Cas-Based Genome Editing Methods. (Review)
Da Eun Yoon, Hyunji Lee† Kyoungmi Kim†. International Journal of Stem Cells 2023 Oct 31;
IF=3.011
Clinical Approaches for Mitochondrial Diseases. (Review)
Seongho Hong, Sanghun Kim, Kyoungmi Kim†, Hyunji Lee†. Cells 2023 Oct 20; 12,2494
IF=7.666
Trends and prospects in mitochondrial genome editing. (Review)
Hong Thi Lam Phan, Hyunji Lee† and Kyoungmi Kim†. Experimental and Molecular Medicine 2023 May 1;
IF=12.172
Enhanced mitochondrial DNA editing in mice using nuclear exported TALE-linked deaminases and nucleases.
Seonghyun Lee*, Hyunji Lee*, Gayoung Baek, Eunji Namgung, Joo Min Park, Sanghun Kim, Seongho Hong and Jin-Soo Kim. Genome Biology 2022 Oct 12; 23:211
IF=17.906
Precision mitochondrial DNA editing with high-fidelity DddA-derived base editors.
Seonghyun Lee, Hyunji Lee, Gayoung Baek and Jin-Soo Kim. Nature Biotechnology 2022 Oct 13; 41:378-386
IF=68.164
Chloroplast and mitochondrial DNA editing in plants.
Beum-Chang Kang, Su-Ji Bae, Seonghyun Lee, Jeong Sun Lee, Annie Kim, Hyunji Lee, Gayoung Baek, Huiyun Seo, Jihun Kim and Jin-Soo Kim. Nature Plants 2021 July 01; 7:899–905,
IF=17.352
Targeted mutagenesis in mouse cells and embryos using an enhanced prime editor.
Soo-Ji Park*, Tae Yeong Jeong*, Seung Kyun Shin*, Da Eun Yoon, Soo-Yeon Lim, Sol Pin Kim, Jungmin Choi, Hyunji Lee, Jeong-Im Hong, Jinhee Ahn, Je Kyung Seong† & Kyoungmi Kim†.Genome Biology 2021 Jun 03; 22:170, IF=17.906
Mitochondrial DNA editing in mice with DddA-TALE fusion deaminases.
Hyunji Lee*, Seonghyun Lee*, Gayoung Baek, Annie Kim, Beum-Chang Kang, Huiyun Seo and Jin-Soo Kim. Nature Communications 2021 Feb 19; 12:1190,
IF=17.690
STAT3-mediated MLST8 gene expression regulates cap-dependent translation in cancer cells.
Hyunji Lee*, Hyunjung Chin*, Hyeyoung Kim, Hosung Jung, Daekee Lee. Molecular Oncology 2020 Jun 29; 14(8):1850-1867,
IF=6.603
Genome editing methods in animal models. (Review)
Hyunji Lee, Da Eun Yoon, Kyoungmi Kim. Animal Cells and Systems 2020 Feb 17; 24(1):8-16,
IF=2.340
Unexpected CRISPR on-target effects. (Review)
Hyunji Lee & Jin-Soo Kim. Nature Biotechnology 2018 July 30; 36:703-704,
IF=68.164
Adenine base editing in mouse embryos and an adult mouse model of Duchenne muscular dystrophy.
Seuk-Min Ryu*, Taeyoung Koo*, Kyoungmi Kim*, Kayeong Lim*, Gayoung Baek, Sang-Tae Kim, Heon Seok Kim, Da-eun Kim, Hyunji Lee, Eugene Chung & Jin-Soo Kim. Nature Biotechnology 2018 Apr 27; 36:536-539,
IF=68.164
Arhgap17, a RhoGTPase activating protein, regulates mucosal and epithelial barrier function in the mouse colon.
So-young Lee, Hwain Kim, Kyoungmi Kim, Hyunji Lee, Seungbok Lee & Daekee Lee. Scientific Reports. 2016 May 27; 6:26923
IF=4.996
ERBB3 knockdown induces cell cycle arrest and activation of Bak and Bax-dependent apoptosis in colon cancer cells.
Hyunji Lee, Hyunjung Lee, Hyunjung Chin, Kyoungmi Kim and Daekee Lee. Oncotarget. 2014 Jul 15; 5:5138-5152
IF=6.359
Epiregulin-dependent amphiregulin expression and ERBB2 signaling are involved in luteinizing hormone-induced paracrine signaling pathways in mouse ovary.
Kyoungmi Kim, Hyunji Lee, David W. Threadgill, Daekee Lee. Biochem Biophys Res Commun. 2011 Feb 11; 405(2):319-24.
IF=3.575